SurgiSeal^®

Superior flexibility and optimal strength.

SurgiSeal^® Topical Skin Adhesive is a high-performance topical skin adhesive designed to offer both clinical efficiency and patient comfort. It is the only topical skin adhesive in the world to receive FDA 510k clearance in demonstrating inhibition of gram-positive and gram-negative bacteria growth¹. Our proprietary formula does not require an initiator to activate and provides a flexible, water-resistant, antimicrobial protective coating.

SurgiSeal^® adhesive has two unique applicator options. The SurgiSeal Stylus^® applicator has 0.5ml of adhesive and offers an ergonomic design. This patented applicator allows for maximum coverage with minimal adhesive material. The original SurgiSeal^® applicator has 0.35ml of adhesive and a wider foam tip that delivers consistent and generous coverage of adhesive.

Features & Benefits

• Inhibition of Bacteria
  SurgiSeal^® is the only topical skin adhesive in the world to receive FDA 510K clearance in demonstrating inhibition of gram positive and gram negative bacteria growth.¹
• High-Strength Formulation
  Made with a 2-octyl cyanoacrylate formulation, which features a greater breaking strength and broader uses in clinical applications than existing n-butyl cyanoacrylates or octyl/butyl blends. ³
• OctylFlex^® Technology
  Our unique formulation provides the optimal balance of properties that matter most to healthcare providers while providing the best clinical outcome for patients: optimal flexibility, broad spectrum antimicrobial protection, an integrated catalyst, adhesive purity, and improved patient comfort.
• Distinct Applicator Options
  Available in multiple formats in both 0.35ml and 0.5ml applicators for tailored application needs.
• In-vitro studies have shown that gram-negative and gram-positive bacteria do not proliferate within the SurgiSeal adhesive. Moreover, SurgiSeal adhesive demonstrates a log reduction of greater than seven in organisms including Methicillin-Resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Corynebacterium pseudodiphtheriticum, Klebsiella pneumoniae, Escherichia coli, and Pseudeomonas Aeruginosa.²
• High Moisture Vapor Transmission Rate (MVTR)
  The proprietary formulation is designed to provide optimal permeability, increasing moisture and oxygen transmission to the wound.
• Rapid Polymerization
  Sets quickly—within minutes—saving time during wound closure procedures.
• Microbial Barrier and Water-Resistant Protection
  SurgiSeal adhesive forms a barrier on the skin, preventing bacteria and water from reaching the wound, reducing the risk of infection and allowing patients to shower immediately.²
• Low Exothermic Reaction
  SurgiSeal adhesive is formulated with 2-octyl-cyanoacrylate, a longer alkyl chain that slows polymerization and minimizes heat release. This controlled reaction helps avoid sudden heat release. SurgiSeal’s low exothermic profile is a deliberate design choice to ensure safety, patient comfort and effectiveness in clinical settings.
• Flexible Without Plasticizers
  Maintains flexibility without added plasticizers, preserving adhesive integrity.

References

¹ https://www.ajicjournal.org/article/S0196-6553(17)30861-1/abstract
² Prince D, Slanki K, Varughese R, et al. Antibacterial effect and proposed mechanism of action of a topical surgical adhesive. Am J Infect Control. 2018;46:26–29. doi.org/10.1016/j.ajic.2017.07.008.
³ Schwade, Nathan D. eMedicine. 2007. WebMD. 17 September 2007, www.eMedicine.com